Methods of fibrose detection in cirrochemical patients
systematic review
DOI:
https://doi.org/10.4322/prmj.2019.031Keywords:
liver cirrhosis, diagnosis, liver diseasesAbstract
Purpose: This study aimed to perform a systematic review of articles published in English, Spanish and Portuguese in the last decade, with a view to research on methods of fibrosis detection in cirrhotic patients. Methods: It was selected studies published from 2013 to 2018. The descriptors used were from ” Liver Cirrhosis “, “Diagnosis” and ” Liver Diseases”. The database bases consulted were MedLine, SciELO, Lilacs and Science Direct. Results: In 13 articles, there was an increase in interest about literature, above all not so many publications about different approaches and different diagnostic methods. Were found 4 articles researching about invasive method (hepatic biopsy), as many as 9 articles were cited non invasive methods, among these, 9 were cited imaging methods e 4 were cited serum methods. Conclusion: Despite the technical benefits described in the literature, new research must be carried out in order to identify methods that are more cost-effective and more accurate. Due to the breadth of methods, fidelity levels and cost, it was possible to report which would be most cost-effective, with ultrasound being a first-line examination. Serum methods were important for monitoring and provided useful patient prognostic information. Still, liver biopsy is considered the “gold standard” of methods for diagnosing liver disease.
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